impossible → routine
The shape of a protein
Getting the three-dimensional shape a protein folds into from its sequence of amino acids.
Impossible
AlphaFold's CASP14 result answers what the assessors had called a 50-year grand challenge in biology.
median 92.4 GDT across all targets
source1 year, 7 months
Routine
Predicted structures for over 200 million proteins are free to search and to bulk-download.
200 million structures, no cost
source